4-chloro-2-hydroxy acetophenone

4-chloro-2-hydroxy acetophenone - Names and Identifiers

Name	4'-Chloro-2'-hydroxyacetophenone
Synonyms	4-CHLORO-2-HYDROXYACETOPHENONE 4-Chloro-2-hydroxyacetophenone 4-chloro-2-hydroxy acetophenone 4'-CHLORO-2'-HYDROXYACETOPHENONE 4'-Chloro-2'-hydroxyacetophenone 1-(4-chlor-2-hydroxyphenyl)ethanone 1-(4-CHLORO-2-HYDROXYPHENYL)ETHANONE 1-(4-chloro-2-hydroxyphenyl)ethanone 1-(4-Chloro-2-hydroxyphenyl)ethan-1-one 1-(4-chloro-2-hydroxyphenyl)ethan-1-one Ethanone, 1-(4-chloro-2-hydroxyphenyl)- 1-(4-Chloro-2-hydroxyphenyl)ethan-1-one, 2-Acetyl-5-chlorophenol
CAS	6921-66-0
EINECS	614-935-2
InChI	InChI=1/C8H7ClO2/c1-5(10)7-3-2-6(9)4-8(7)11/h2-4,11H,1H3

4-chloro-2-hydroxy acetophenone - Physico-chemical Properties

Molecular Formula	C8H7ClO2
Molar Mass	170.59
Density	1.298±0.06 g/cm3(Predicted)
Melting Point	27-30°C
Boling Point	120-122°C 10mm
Flash Point	116.1°C
Vapor Presure	0.00468mmHg at 25°C
pKa	9.20±0.10(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.5750 to 1.5790
MDL	MFCD00238557

4-chloro-2-hydroxy acetophenone - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	R22 - Harmful if swallowed R37/38 - Irritating to respiratory system and skin. R41 - Risk of serious damage to eyes
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection.

4-chloro-2-hydroxy acetophenone - Introduction

4 '-Chloro-2'-hydroxyacetophenone is an organic compound with the formula C8H7ClO2 and a molecular weight of 170.59g/mol. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
- 4 '-Chloro-2'-hydroxyacetophenone is a white crystalline solid.
-It is stable at room temperature and not volatile.
-The compound is insoluble in water, but soluble in organic solvents such as ethanol, ether and chloroform.

Use:
- 4 '-Chloro-2'-hydroxyacetophenone is used as an important intermediate in organic synthesis.
-It can be used to synthesize other organic compounds, such as drugs, dyes and pesticides.
-The compound also has biological activities such as antibacterial, antioxidant and anti-inflammatory, so it is also used in the field of medicine.

Preparation Method:
The synthesis method of -4 '-Chloro-2'-hydroxyacetophenone can be achieved by the hydrochloric acid esterification reaction of benzophenone, and then the hydroxylation reaction.
-Specific synthetic methods can be consulted in chemical synthesis manuals or professional research papers.

Safety Information:
- 4 '-Chloro-2'-hydroxyacetophenone has low toxicity, but attention should be paid to rational use and storage.
-Wear appropriate personal protective equipment such as gloves and goggles when using.
-Avoid direct contact with skin and eyes, and avoid inhalation or ingestion of the compound.
-When using or storing, keep it away from fire and high temperature environment.
-If it enters the eyes or skin by accident, rinse immediately with plenty of water and seek medical help. If ingested by accident, seek medical attention promptly.

Last Update：2024-04-09 15:17:59